The Director of the Oklahoma Bureau of Narcotics (OBN) is warning the public about a new and deadly synthetic opioid that has now been confirmed in Oklahoma.

OBN Director Donnie Anderson says Cychlorphine, known scientifically as N-Propionitrile chlorphine, has been found in Oklahoma, and linked to at least one overdose death involving an 18-year-old from Yukon.

“Cychlorphine can be up to ten times stronger than Fentanyl. Though it is a synthetic opioid, this drug is extremely powerful, and Naloxone may not be effective in reversing an overdose. At the very least, it might take multiple doses to bring someone back from an overdose,” Director Donnie Anderson said.

More than two dozen states have reported overdoses and deaths linked to Cychlorphine since it began to emerge in the United States in late 2024. The drug is believed to be sourced into the United States from Europe and Asia. Criminal manufacturers often press Cychlorphine into colorful pills that can look like legitimate pharmaceuticals or add various stamps to resemble Ecstasy tablets.

Director Anderson says Cychlorphine is one of many variations of black-market synthetic opioids that have made their way into the United States and onto Oklahoma streets over the past decade.

“Criminal manufactures commonly change their formulas to increase profit and potency, as well as evade new drug laws. We’ve seen modifications of fentanyl, multiple variations of the synthetic opioid, Nitazine, and we have already seen new forms of Cychlorphine in Oklahoma,” Anderson said.

OBN is going to be working with the State Board of Pharmacy and the Oklahoma legislature to ban Cychlorphine, as well as educate the public about the constant emergence of potentially deadly drugs.

“With so many new and powerful drugs surfacing every day, there has never been a more dangerous time in our culture to be a recreational drug user. People don’t know what they are buying and they put their very lives at risk every time they use,” Anderson said.

Citizens can anonymously report suspected drug and human trafficking activity to OBN by sending a Facebook DM or calling the OBN Tip Line at 800-522-8031.